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Professor Mikko Sams from Department of Neuroscience and Biomedical Engineering Aalto University, Finland is guest professor at MIB this fall and will give a talk on Mismatch Negativity.
14.09.2016 |
| Dato | man 07 nov |
| Tid | 13:30 — 14:30 |
| Sted | Meeting room 5th floor, Building 10G, Aarhus University Hospital, Nørrebrogade |
Title:
Early years of N100 and Mismatch Negativity Response in human auditory neuroscience
Abstract:
Presentation of auditory stimuli triggers a sequence of responses in the brain, which can be recorded non-invasively with electro- (EEG) and magnetoencephalography (MEG). After response-averaging become possible in 1970s, event-related EEG responses provided a fascinating window to the processing of sounds in the human auditory system. Very soon introduction of MEG provided a new tool for auditory neuroscientists, especially because of its superiority in localizing neural sources of event-related responses. From early years, event-related responses have been used in assessing how the auditory system discriminates between different stimulus features, first using stimulus-specific adaptation of the N100 deflection, and later using the mismatch negativity response (MMN). MMN is a specific response to a infrequent auditory event presented among repeating ones. Even now much of the human auditory neuroscience uses, very successfully, N100 and MMN as its major tools. In my talk, I will present my personal view of the early years using these great responses in understanding human brain functions, starting with our 2-channel EEG recordings but leading quite quickly to 306-channel MEG recordings.