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PhD defence: Henrique Fernandes

The project shows how measures of brain structure and function can be combined with computational connectomics to produce fingerprints of the human brain in health and disease.

13.01.2016 | Hella Kastbjerg

Dato ons 10 feb
Tid 14:00 16:00
Sted Aarhus University Hospital, Patologisk Auditorium, Building 18.

Title:
Rebalancing the brain: Using computational connectomics to fingerprint the human brain in health and disease.

Abstract:
Brain disease has been widely associated with unbalanced neural network organisation, which drives disruption of integrative processing. The early consequences of neurobiological disturbances in neuropsychiatric disorders remains however not well understood.

This PhD project proposes a new methodological framework to elucidate the fundamental principles of brain functioning in health and disease. The research has led to the identification of new potential clinical biomarkers for early stages of bipolar disorder, and a novel fingerprinting method was developed to identify the optimal fingerprint of stimulation underlying a successful outcome of deep brain stimulation for chronic pain. Furthermore, the research also identified a new metric to evaluate the capacity of each brain region to bind information over time, which long-term could make a major contribution to our understanding of how the processing of information in functional and structural networks contribute to the unbalanced brain states found in neuropsychiatric disorders.

The defense is public and everyone is welcome.

After the defence Center for Music in the Brain hosts a reception.

Ph.d.-forsvar, Musicinthebrain, Forskning, Alle grupper, Musicinthebrain