Understanding disease and health in HD: A structural biology approach on proteins causing bacterial infections
2016.01.27 |
Date | Mon 01 Feb |
Time | 14:15 — 16:00 |
Location | The AIAS Auditorium, Buliding 1632, Høegh-Guldbergs Gade 6B, 8000 Aarhus C |
What is the molecular basis of life, health and disease? Proteins are the workhorses of all biological processes in living organisms. Their form (structure) and correct function are crucial for our health and all biological processes. Wrong protein forms (amyloids) are non-functional and are reasons for several diseases, such as Alzheimer’s and Parkinson’s. It is of great importance to know the structures of proteins to be able to understand the origins of diseases, but in general the origin of health.
As a first step to understand the fundamentals of bacterial infections and possible ways of preventing them, I have determined the first HD structures. I will present these results on bacteria and biofilms, with a general emphasis on structural biology and how it functions.
Ümit Akbey is an AIAS-COFUND Junior Fellow and Assistant Professor at Aarhus University. He earned his Ph.D. at Max Planck Institute for Polymer Research in polymer Nuclear Magnetic Resonance spectroscopy in Mainz Germany, on structural characterization of advanced functional materials. He then started his structural biology work at the Leibniz Institute for Molecular Pharmacology in Berlin. He joined Aarhus University in 2014, where he is working at iNano center and Department of Chemistry, as well as AIAS. His current research focuses on NMR-supported structural biology on insoluble proteins mediating bacterial infections.
The AIAS Fellows' Seminar is a session of seminars held by the AIAS fellow or by other speakers proposed by the fellows. In each seminar, one fellow will present and discuss his/her current research and research project, closing off with a question and discussion session.
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