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Experiments on mice will make us wiser about kidney failure and transplantation

Why is the secretion of protein increased in kidney patients when the disease worsens? And how do we avoid damage to transplanted kidneys? This is what Henrik Birn, who is a new professor at Aarhus University, investigates.

2021.09.09 | Lene Halgaard

Henrik Birn sees the professorship as an opportunity to combine experimental and clinical research, so that the results from the laboratory can benefit patients as much as possible. Photo: Jens Thaysen

Despite the fact that kidney patients receive treatment, their kidney disease often worsens over time and can end in kidney failure. Through his research, Henrik Birn, who is a new professor at the Department of Clinical Medicine, aims to uncover why this is so.

Henrik Birn translates results from mouse studies into an understanding of different types of damage to the kidneys. In addition, he conducts clinical examinations of kidney patients and patients who have undergone kidney transplants at Aarhus University Hospital, where he is also employed as a consultant. Experiments with mice have shown that increased excretion of proteins exacerbates the damage to the kidneys, which is also the case in the patients. Therefore, Henrik Birn also concentrates his research on new medicines that have a positive effect on kidney patients so they avoid kidney failure and dialysis.

The goal is to develop advanced kidney treatments with better use of existing and new forms of treatment. This will also benefit patients with transplanted kidneys and ensure these function for as long as possible.

Contact

Professor, PhD, Consultant Henrik Birn
Aarhus University, Department of Clinical Medicine and
Aarhus University Hospital, Department of Renal Medicine
Mail: hb@ana.au.dk
Mobile: (+45) 6171 7870

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