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The article, written by Prof. Marco Capogna in collaboration with two well-known experts from New York, is entitled: "The ins and outs of inhibitory synaptic plasticity: neuron types, molecular mechanisms and functional roles".
2020.09.28 |
Left: the structure of a cortical GABAergic neuron, middle: potentiation of an inhibitory GABAergic synaptic current, right: three “blue” inhibitory GABAergic eurons as part of a memory engram.
This article provides an overview of inhibitory synaptic plasticity (ISP) in the hippocampus and neocortex. First, the article illustrates GABAergic neurons’ diversity. Then, it presents the main molecular mechanisms underlying ISP. Finally, the paper discusses the role of ISP on neuronal circuits and memory engrams. The article is part of a special issue review on “Proteins and Circuits in Memory” published by the European Journal of Neuroscience.
Link to publication:
https://onlinelibrary.wiley.com/doi/epdf/10.1111/ejn.14907