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Oxytocin Receptor Exon III Methylation in the Umbilical Cord Blood of Newborns With Prenatal Exposure to Crack Cocaine

In a recent paper Rodrigo Grassi-Oliveira and colleagues analyzed DNA methylation patterns of two genomic loci located in exon III of the Oxytocin Receptor (OXTR) gene (OXTR1 and OXTR2) in the umbilical cord blood (UCB) of newborns with a history of crack cocaine exposure in utero. Regression analyses showed that maternal addiction severity for crack cocaine use predicted OXTR1 DNA methylation in newborns.

2021.06.04 | Karen Jul Madsen

Rodrigo Grassi-Oliveira

Rodrigo Grassi-Oliveira

Read the full article in Frontiers in Cell and Developmental Biology:

Oxytocin Receptor Exon III Methylation in the Umbilical Cord Blood of Newborns With Prenatal Exposure to Crack Cocaine

Baptista Talita, de Azeredo Lucas Araújo, Zaparte Aline, Viola Thiago Wendt, Coral Sayra Catalina, Nagai Maria Aparecida, Mangone Flávia Rotea, Pavanelli Ana Carolina, Schuch Jaqueline B., Mardini Victor, Szobot Claudia M., Grassi-Oliveira Rodrigo

In Frontiers in Cell and Developmental Biolog, vol. 9, 4 June 2021

doi.org/10.3389/fcell.2021.639287

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