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Real-time dose reconstruction and dose guidance during radiotherapy delivery
2021.11.11 |
| Date | Fri 26 Nov |
| Time | 15:00 — 17:00 |
| Location | Auditorium C114-101, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, Entrance C, level 1, 8200 Aarhus N |
On Friday 26 November at 15:00, Casper Gammelmark Muurholm defends his PhD dissertation entitled "Real-time dose reconstruction and dose guidance during radiotherapy delivery".
In radiotherapy, tumor motion can deteriorate the intended dose distribution. The dosimetric consequences are usually unknown for each individual fraction, but with real-time motion-including dose reconstruction these consequences can be investigated during patient treatments. In this Ph.D.-project the dose reconstruction is done using a computer program called DoseTracker, which has been developed at Aarhus University Hospital. In the first part of the project, DoseTracker was expanded to include rotational motion which can happen during radiation of e.g. the prostate. The program was tested experimentally in a manner which mimics actual patient treatments. The reconstructed doses were compared with dosimetric measurements performed simultaneously. The second part of the project was about the development of a novel method for evaluation of the radiation delivery using the aforementioned realtime dose reconstructions as well as a prediction of the yet to be delivered dose based on the motion patterns of the target. The method was tested in simulations as an evaluation tool and used as a part of a novel dose-based patient position optimization strategy.
The summary is written by the PhD student.
The defence is public and takes place in Auditorium C114-101, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, Entrance C, level 1, 8200 Aarhus N. Please read the attached press release for more information.
PhD student Casper Gammelmark Muurholm
Mail: casmuu@oncology.au.dk
Phone: (+45) 50599924