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Long-term bowel dysfunction following right-sided hemicolectomy for colon cancer
2021.10.07 |
| Date | Wed 27 Oct |
| Time | 15:30 — 17:30 |
| Location | Auditorium B (G206-142), Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N and online |
On Wednesday 27 October at 15:30, Helene Mathilde Larsen defends her PhD dissertation entitled "Long-term bowel dysfunction following right-sided hemicolectomy for colon cancer".
The group of colon cancer survivors is increasing, which demands focus on life beyond cancer. Colon cancer survivors may suffer from several long-term sequelae following their cancer treatment including bowel dysfunction. A study leading up to this PhD project showed that 16% of right-sided colon cancer patients suffered from long-term diarrhoea, which affected their quality of life. In order to improve quality of life after cancer there is a growing need for investigating the frequency, underlying pathophysiology and management of bowel dysfunction.
In this PhD project long-term bowel dysfunction, and especially diarrhoea, following colon cancer treated with a right-sided hemicolectomy was investigated. The clinical evaluation and treatment of this patient group was studied in the Late Sequelae Clinic at Aarhus University Hospital. The effect of a survey to screen colon cancer survivors for bowel dysfunction was evaluated along with the management of patients referred through the screening survey. Based on a group of patients with and without chronic diarrhoea following right-sided hemicolectomy, the underlying causes of diarrhoea was studied. Bile acid malabsorption and bacterial overgrowth in the small bowel were investigated as possible causes. The results suggest that colon cancer survivors benefit from systematic management of long-term bowel sequelae.
The summary is written by the PhD student.
The defence is public and takes place in Auditorium B (G206-142), Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, Aarhus N and online via Zoom. Please read the attached press release for more information.
PhD student Helene Mathilde Larsen
Mail: hemala@clin.au.dk
Phone: (+45) 60101648