- Education
-
Research
Current research
Talent
-
Collaboration
Businesses
Government agencies and institutions
Alumni
-
About AU
Organisation
Job at AU
Noradrenergic mechanisms in motor and non-motor symptoms of Parkinson’s disease
2021.09.29 |
| Date | Fri 15 Oct |
| Time | 14:00 — 16:00 |
| Location | Conference room G206-124, entrance G, G206, Aarhus University Hospital and online |
On Friday 15 October at 14.00, Martin Byskov Kinnerup defends his PhD dissertation entitled "Noradrenergic mechanisms in motor and non-motor symptoms of Parkinson’s disease".
Parkinson's disease is characterized by the aggregation of misfolded α-synuclein, which aggregates and leads to neuronal dysfunction and death. α-synuclein aggregates may affect brainstem noradrenergic nuclei prior to midbrain dopaminergic nuclei in some patients. The early loss or dysfunction of noradrenaline neurons may play a role in motor symptoms and early non-motor symptoms in Parkinson's disease.
In the present thesis motor and non-motor symptoms and the early changes in noradrenaline is assessed with clinical assessments and PET-imaging. The aim of the thesis is to elucidate the role of noradrenaline in motor and non-motor symptoms. The thesis shows that Parkinson's disease patients with rest tremor have a higher preservation of noradrenaline neurons.
The summary is written by the PhD student.
The defence is public and takes place in Conference room G206-124, Indg. G, G206, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200Aarhus N and online. Please read the attached press release for more information.
PhD student Martin Byskov Kinnerup
Mail: M3Kinnerup@clin.au.dk
Phone: +45 28405383