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PhD defence: Randi Istrup Juul

Characterization and use of DNA positions that are recurrently mutated across cancer patients

2021.11.17 | Graduate School of Health

Date Fri 10 Dec
Time 10:00 12:00
Location The ground floor auditorium, Department of Molecular Medicine, Aarhus University Hospital, Brendstrupgårdsvej 21A, 8200 Aarhus N and online

On Friday 10 December at 10:00, Randi Istrup Juul defends her PhD dissertation entitled "Site-specific hotspots recurrently mutated across cancer – A genome-wide pan-cancer screen for non-coding drivers and the potential use in ctDNA detection".

Cancer is the leading cause of death both world-wide and in Denmark. It is important to diagnose cancer in as early a stage as possible as it usually results in a better prognosis for the patient. Furthermore, it will be advantagous to be able to offer already existing treatments to more patients. The overall aim of this PhD project was to find and characterize positions in the DNA that are recurrently mutated across cancer patients. We sought to identify gen-regulating cancer-causing mutations among these positions, which potentially could allow inclusion of further patients in existing treatments. Furthermore, we investigate if such positions can be used to identify cancer at early stages using a blood sample.

The summary is written by the PhD student.

The defence is public and takes place in the ground floor auditorium, Department of Molecular Medicine, Aarhus University Hospital, Brendstrupgårdsvej 21A, 8200 Aarhus N and online. Please read the attached press release for more information.

Contact:

PhD student Randi Istrup Juul

Mail: randi.istrup@clin.au.dk

Phone: (+45) 78455310

Read full press release

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