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Retinal oximetry in retinal vein occlusion
2021.06.04 |
| Date | Thu 01 Jul |
| Time | 14:00 — 16:00 |
| Location | Aarhus University Hospital, Palle Juul-Jensens Boulevard, Aarhus N and online |
On Thursday 1 July at 14.00, Signe Krejberg Jeppesen defends her PhD dissertation entitled "Retinal oximetry in retinal vein occlusion".
Occlusion of larger retinal venules (RVO) is a frequent cause of visual impairment and blindness in Denmark. The occlusion arrests the blood supply to a retinal area affected by the occlusion which results in hypoxia and release of vascular endothelial growth factor. The visual prognosis depends on the duration of hypoxia and the size of the occlusion affected retinal area. The severity of the occlusion is expressed by the degree of ischaemia, but visual acuity measurements has been shown to be a better predictor for visual prognosis than the degree of ischaemia. This may be due to difficulties in quantifying retinal ischaemia. However, reduced blood flow results in retinal hypoxia which in recent years has become measurable by retinal oximetry. The examination is based on ordinary fundus photography recorded at two different wavelengths. On the basis of differences in light absorption from oxygenised and deoxygenised blood, the reflectance from the vessels at these two wavelengths can be transformed to oxygen saturation quantification in larger retinal vessels.
The development of this method and the clinical value of retinal oximetry and Doppler coherence tomography are the topics of this PhD study. The oxygen saturation in larger retinal vessels is studied in healthy individuals and in RVO patients in order to elucidate the potential of improvement in retinal oximetry, describe the oxygen saturation in RVO patients, and study the predictive value of retinal oximetry.
The summary is written by the PhD student.
The defence is public and takes place Aarhus University Hospital, Palle Juul-Jensens Boulevard, Aarhus N and online. Please read the attached press release for more information.
PhD student Signe Krejberg Jeppesen
Mail: signekj@clin.au.dk
Phone: (+45) 25 12 01 42