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Exploring the Immunophenotype and Protein Expression Profile of Leukemic Stem Cells in Childhood Acute Myeloid Leukemia
2021.06.04 |
| Date | Fri 18 Jun |
| Time | 14:00 — 16:00 |
| Location | Aarhus University Hospital, Palle Juul-Jensens Boulevard, Aarhus N and online |
On Friday 18 June at 14.00, Marianne Agerlund Petersen defends her PhD dissertation entitled "Exploring the Immunophenotype and Protein Expression Profile of Leukemic Stem Cells in Childhood Acute Myeloid Leukemia".
AML is a heterogeneous neoplasm characterized by a high degree of immunophenotypic and genetic variation. In the past decades, identification of proteins such as aberrant surface antigens expressed by leukemic blasts and stem cells has been ongoing as such proteins may potentially serve as specific targets for future therapeutic agents. In this PhD, the immunophenotype of CD34+CD38– stem cells from pediatic AML patients were investigated using flow cytometry and compared to hematopoietic stem cells from hematologically healthy children. In addition, proteomic profiling of purified stem and blast cells from children with AML was analyzed and compared with purified hematopoietic stem and progenitor cells subsets from healthy children.
The summary is written by the PhD student.
The defence is public and takes place at Aarhus University Hospital, Palle Juul-Jensens Boulevard, Aarhus N and online. Please read the attached press release for more information.
PhD student Marianne Agerlund Petersen
Mail: marianne.agerlund@clin.au.dk
Phone: (+45) 24604987