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Professor and medical specialist in infectious diseases Trine Hyrup Mogensen from Aarhus University and Aarhus University Hospital investigates why apparently healthy young and middle-aged people in some cases develop severe Covid-19 requiring intensive hospitalisation and may experience serious courses of illness or even death.
2021.04.22
What role do genetic factors play in the immune system's ability to detect viruses at an early stage and initiate an adequate immune response to fight e.g. the coronavirus? This is one of the questions that Trine Hyrup Mogensen and her research team are investigating in a new research project, which the Novo Nordisk Foundation supports with a Clinical Distinguished Investigator Grant of DKK 10 million.
According to Trine Hyrup Mogensen, a proportion of the most severe Covid-19 cases can be explained by genetic defects in the patients’ immune system. As the only Danish researcher, she has participated in an international research consortium that examines what genetics and immunology mean for susceptibility and the course of the disease in the case of Covid-19.
And it is this research that Trine Hyrup Mogensen now has the opportunity to continue to expand on. She hopes to generate knowledge that can contribute to an earlier and far better treatment of the people who are particularly severely affected by Covid-19. The new knowledge can furthermore be used to improve the existing vaccine strategies.
Professor, DMSc & Medical Specialist Trine Hyrup Mogensen
Aarhus University, Deparment of Biomedicine and
Aarhus University Hospital, Department of Infectious Diseases
Mobile: (+45) 20 12 52 80
Email: trine.mogensen@biomed.au.dk