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Virtual PhD defence: Asbjørn Graver Petersen

Protective role of KCa3.1 ion channel blockers in animal models of acute respiratory distress syndrome

2021.03.03 | Graduate School of Health

Date Mon 15 Mar
Time 17:00 19:00
Location Online

On Monday 15 March at 17.00, Asbjørn Graver Petersen defends his PhD dissertation entitled "Protective role of KCa3.1 ion channel blockers in animal models of acute respiratory distress syndrome".

Acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in critically ill patients and is characterized by increased permeability of the alveolar-capillary barrier. The delicate structure of the alveolar-capillary barrier is tightly regulated by ion channels, but damage to the lung can disrupt these processes and lead to acute onset of pulmonary edema, hypoxemia, and a need for respiratory support. At present, effective pharmacotherapy for ARDS remains limited, but the discovery of new targets in the alveolar endothelial and epithelial barriers sparks optimism. This PhD project explores the role of two ion channels; namely, calcium-activated potassium channel of intermediate conductance (KCa3.1) and the cystic fibrosis transmembrane conductance regulator (CFTR) channel, and investigates their therapeutic potential in a series of pre-clinical studies.

The summary is written by the PhD student.    

The defence is public and takes place online. Please read the attached press release for more information.


PhD student Asbjørn Graver Petersen

Mail: aspe@biomed.au.dk 

Phone: (+45) 30293574

Please read full press release.

PhD defense, PhD students, Health, Graduate School of Health, Public/Media, Graduate School of Health, Academic staff, Department of Biomedicine