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Influence of Commonly used Vasopressors on Cerebral Circulation, Microcirculation and Oxygenation: Studies in Patients with Brain Tumors using MRI and PET
2021.02.22 |
| Date | Fri 19 Mar |
| Time | 14:00 — 16:00 |
| Location | Online via Zoom |
On Friday 19 March at 14:00, Klaus Ulrik Koch defends his PhD dissertation entitled "Influence of Commonly used Vasopressors on Cerebral Circulation, Microcirculation and Oxygenation: Studies in Patients with Brain Tumors using MRI and PET".
On a daily basis, large amount of vasopressors are administered during anesthesia in neurosurgical patients to avoid decreasing blood pressure during anesthesia and to secure a sufficient cerebral circulation and oxygenation. Phenylephrine and Ephedrine are frequently used vasopressors with different mechanism of action. Earlier studies have indicated that Phenylephrine decreases cerebral oxygenation compared to Ephedrine. In this PhD-study MRI and PET was used to examine the effects of the above mentioned vasopressors analyzing parameters on cerebral macro- and microcirculation, and oxygenation during anesthesia. The PhD-study contributes new knowledge especially on brain microcirculation in relation to the use of vasopressors, and adds clinical practice to theory. The study recommends further research and cautiously makes recommendations on the use of vasopressor therapy when treating low blood pressure during general anesthesia in patients with brain tumors.
The summary is written by the PhD student.
The defence is public and takes place online via Zoom (https://aarhusuniversity.zoom.us/j/66339417762). Please read the attached press release for more information.
PhD student Klaus Ulrik Koch
Mail: klauskoch@clin.au.dk
Phone: (+45) 61686674