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Novel tools for design and delivery of genome-editing components
2021.05.11 |
| Date | Fri 28 May |
| Time | 09:30 — 11:30 |
| Location | Online |
On Friday 28 May at 09:30, Mads Valdemar Anderson defends his PhD dissertation entitled "Lentiviral Ribonucleoprotein Transduction of CRISPR/Cas9 and in silico Design Tool for Prime Editing".
The initial adaptation of the genetic scissors CRISPR/Cas9 triggered an explosive growth in the field of genome-editing and launched gene therapy into a new era. In the last decade, revolutionary discoveries have enabled researchers to perform precise "genetic surgery". However, with these technological advances come new challenges, as previously established methods for delivery of gene therapies are unfit for these emerging tools. The recently described Prime Editing technology directly writes genetic information into a desired DNA site, providing researchers with a "search-and-replace" genome-editing tool. While promising, the many degrees of freedom in designing Prime Editing experiments complicate the design. During his PhD project, Mads Valdemar Anderson has developed new tools for delivery of CRISPR/Cas9 and design of Prime Editing experiments, enabling faster adoption of this promising technology.
The summary is written by the PhD student.
The defence is public and takes place online. Please read the attached press release for more information.
PhD student Mads Valdemar Anderson
Mail: madsanderson@gmail.com