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Children born with a hole in the heart suffer poorer health throughout their lives

A study of all Danish registers for children born with a hole in the heart – actually a gap between the atrial chambers – shows that the heart defect has consequences for their health throughout their lives. The study is part of Camilla Nyboe's higher doctoral dissertation from Aarhus University.

2021.10.20 | Lene Halgaard

Newly-appointed Doctor of Medical Science Camilla Nyboe is a medical doctor at Aarhus University Hospital. She hopes that new knowledge about ASD patients will make improved treatment and follow-up possible. Photo: Lorentzen Fotografi

Every year, one child in a thousand is born with a hole between the atrial chambers of the heart. Some children have the hole closed by surgery, while others live without any intervention.

New Doctor of Medical Science Camilla Nyboe from the Department of Clinical Medicine at Aarhus University has examined the Danish registers for the years between 1954–2011 to find all Danish patients with what is commonly called a hole in the heart – or in medical terminology, atrium septal defect (ASD).

In her higher doctoral dissertation, Camilla Nyboe concludes that the ASD patients have higher mortality, a greater risk of arrhythmia (irregular heart rhythm), mental disorders, a lower level of education and a greater chance of ending up on an early retirement pension compared to the Danish population in general.

The ASD patients also have a higher risk of reduced quality of life regardless of which treatment they received. Nonetheless, Camilla Nyboe concludes in her higher doctoral dissertation that surgery that closes the hole improves the health of the patients.

Contact

DMSc & PhD Camilla Nyboe
Aarhus University, Department of Clinical Medicine and
Aarhus University Hospital, Department of Cardiothoracic and Vascular Surgery
Mobile: (+45) 2095 9903
Email: camilla@nyboe.nu

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