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Associate Professor receives millions for research into the body's fluid balance

Lene N. Nejsum, associate professor at Aarhus University, receives a Hallas-Møller Ascending Investigator Grant from the Novo Nordisk Foundation towards her research into the regulation of body water balance. The new grant provides DKK ten million in funding for her research over the next five years.

2020.04.03 | Sabina Bjerre Hansen

Lene N. Nejsum

Lene N. Nejsum from the Department of Clinical Medicine has just received a grant of DKK 10 million from the Novo Nordic Foundation. Photo: Private.

Several diseases, including chronic kidney disease and congestive heart failure, are associated with dysregulation of body water balance in the form of either dehydration or water retention. The kidneys, and in particular the water channel protein Aquaporin-2, play vital roles in regulation of body water balance via fine-tuning the urine concentration. And it is precisely the Aquaporin 2-protein that Lene N. Nejsum will now be studying more closely.

She and her research colleagues use newly-developed methods within bioimaging, which enable them to visualize the small Aquaporin-2 vesicles in kidney cells, with the hope of increasing our understanding of the physiological mechanisms that regulate the protein. Improved understanding of this could contribute towards developing of treatments that can sustain body water balance.

Lene N. Nejsum will use the grant from the Novo Nordisk Foundation to employ an assistant professor and two PhD students, as well as for technical assistance and purchase of equipment.

Contact

Associate Professor, PhD Lene N. Nejsum
Aarhus University, Department of Clinical Medicine
Mobile: (+45) 21 16 31 21
Email: nejsum@clin.au.dk

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