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Circulatory support in neonatal resuscitation
2022.01.10 |
| Date | Fri 14 Jan |
| Time | 14:00 — 16:00 |
| Location | Online and in Auditorium C114-101, Entrance C, level 1, Aarhus University Hospital, Palle Juul-Jensens Boulevard, Aarhus N |
On Friday 14 January at 14:00, Hannah Brogård Andersen defends her PhD dissertation entitled "Circulatory support in neonatal resuscitation".
Epinephrine (adrenaline) is a mainstay in international neonatal resuscitation guidelines. However, despite its ubiquity and decades of research, the effect and safety of resuscitation with epinephrine remains controversial. In animal studies, epinephrine increases the chance of achieving return of spontaneous circulation (ROSC). This positive short-term effect may however be counterbalanced by a risk of harm. Animal studies have proposed adverse effects of epinephrine on myocardial function and cerebral microvascular blood flow, which leave us asking whether epinephrine improves short term survival but at the cost of poor long-term outcomes, including neurologic outcome. Thus, to improve outcomes after cardiac arrest in newborns, the aim of this project was to investigate the effect of resuscitation with epinephrine vs placebo in two different piglet models of newborn cardiac arrest (hypoxia and hypoxia combined with infection) with emphasis on ROSC and imaging biomarkers of brain damage.
The summary is written by the PhD student.
The defence is public and takes place in Auditorium C114-101, Entrance C, level 1, Aarhus University Hospital, Palle Juul-Jensens Boulevard, Aarhus N and online via Zoom Please read the attached press release for more information.
PhD student Hannah Brogård Andersen
Mail: hannah.brogaard@clin.au.dk
Phone: (+45) 27134248