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Advanced stage epithelial ovarian cancer - Aspects of preoperative imaging and cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC)
2020.12.10 |
| Date | Fri 08 Jan |
| Time | 15:00 — 17:00 |
| Location | Auditorium G206-142, Aarhus University Hospital, Palle Juul Jensens Boulevard and online via Zoom |
On Friday 8 January at 15.00, Mette Schou Mikkelsen defends her PhD dissertation entitled "Advanced stage epithelial ovarian cancer - Aspects of preoperative imaging and cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC)".
Each year approximately 500 Danish women are diagnosed with ovarian cancer, among which epithelial ovarian cancer (EOC) is the far most common subtype. Unfortunately, three-quarters of women diagnosed with EOC present with advanced stage disease, which is frequently characterized by diffuse peritoneal metastatic spreading. Women with advanced stage EOC have a poor prognosis, which is the main reason why research aiming to improve diagnostics and treatment of EOC is highly warranted. Existing literature indicates that cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) might have a place in the treatment of EOC. In this PhD project three clinical studies were performed. The main topics explored within the studies were 1) preoperative imaging used for assesment of peritoneal dissemination in advanced stage EOC, 2) pharmacokinetics of carboplatin used in HIPEC, and 3) short-term morbidity and mortality after cytoreductive surgery with carboplatin HIPEC used in treatment of advanced stage EOC.
The summary is written by the PhD student.
The defence is public and takes place in auditorium G206-142, Aarhus University Hospital, Palle Juul Jensens Boulevard 99, 8200 Aarhus N and online via Zoom. Please read the attached press release for more information.
PhD student Mette Schou Mikkelsen
Mail: mettesmikkelsen@clin.au.dk
Phone.: +45 51200373