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Professor develops new treatment for infertile women

Karin Lykke-Hartmann is Aarhus University’s new professor of reproductive medicine. Her work involves studying the genes found in the ovaries in the hope of being able to stimulate the maturation of women’s eggs. If she succeeds, this will be good news for the many infertile women who do not benefit from the traditional hormonal fertility treatment.

2021.08.23 | Sabina Bjerre Hansen

Karin Lykke-Hartmann took up her professorship at the Department of Biomedicine on 1 August 2021. Photo: Simon Byrial Fischel, AU Health.

Karin Lykke-Hartmann took up her professorship at the Department of Biomedicine on 1 August 2021. Photo: Simon Byrial Fischel, AU Health.

Traditional treatment of women who cannot have children includes hormone treatment. This treatment is associated with a number of side-effects, and far from all women actually become pregnant despite enduring the physical discomfort caused by the treatment.

Karin Lykke-Hartmann is focused on finding new signal pathways in women’s ovaries which can stimulate the maturation of eggs in infertile women. She examines molecular mechanisms using genetic and cytobiological techniques, and together with her research colleagues she has generated the knowledge needed to develop new medicines.

The newly-appointed professor and her team have identified a new signal path in the ovaries with the help of mouse models and subsequently demonstrated the effect in human tissue. The next step is to demonstrate the effect in larger animals such as e.g. sheep, which has an ovary anatomy and physiology that resembles that of humans.

Contact
Professor & PhD Karin Lykke-Hartmann
Aarhus University, Department of Biomedicine and
Aarhus University Hospital, Department of Clinical Genetics
Mobile: (+45) 29 39 05 58
Email: kly@biomed.au.dk

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