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The neurovascular system and general inflammation
2021.08.03 |
| Date | Wed 18 Aug |
| Time | 16:00 — 18:00 |
| Location | Samfundsmedicinsk Auditorium, Aarhus University, Bartholins Allé 2, building 1262, 8000 Aarhus C |
On Wednesday 18 August at 16:00, Signe Kirk Fruekilde defends her PhD dissertation entitled "Longitudinal imaging of cerebrovascular dynamics in awake mice using optical techniques".
Neurons are extremely vulnerable to starvation. Therefore, a well-functioning vascular system that provides nutrients and oxygen, and removes waste, is crucial for maintaining a healthy cerebral environment.
This defence will describe the process of designing an experimental setup and analysis protocol, which allowed for a longitudinal investigation of the cerebral vascular system in mice. Overall, we revealed how a severe systemic inflammation caused a disturbance in the normal flow of blood within the capillary network. These findings are discussed as a potential danger to neuronal health, since demands of oxygen and nutrition may not be met by the vascular system during inflammation. The potential of the developed protocols extends beyond inflammation to many questions related to the health and resilience of the cerebrovascular system.
The summary is written by the PhD student.
The defence is public and takes place in Samfundsmedicinsk Auditorium, Aarhus University, Bartholins Allé 2, building 1262, 8000 Aarhus C. Please read the attached press release for more information.
PhD student Signe Kirk Fruekilde
Mail: skf@cfin.au.dk
Phone: (+45) 28253176